Pancreatic beta-cells: From generation to regeneration
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چکیده
منابع مشابه
Pancreatic beta-cells: from generation to regeneration.
The pancreas is composed of two main compartments consisting of endocrine and exocrine tissues. The majority of the organ is exocrine and responsible for the synthesis of digestive enzymes and for their transport via an intricate ductal system into the duodenum. The endocrine tissue represents less than 2% of the organ and is organized into functional units called islets of Langerhans, comprisi...
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Diabetes mellitus results from inadequate mass of insulin-producing pancreatic beta cells. Type 1 diabetes is characterized by absolute loss of beta cells due to autoimmune-mediated destruction. Type 2 diabetes is characterized by relative deficiency of beta cells due to lack of compensation for insulin resistance. Restoration of deficient beta cell mass by transplantation from exogenous source...
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ژورنال
عنوان ژورنال: Seminars in Cell & Developmental Biology
سال: 2010
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2010.07.007